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PTEN mouse Monoclonal Antibody(9E8), 100ul Liquid Handling &Storage This protein is overexpressed in

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PTEN mouse Monoclonal Antibody(9E8), 100ul Liquid Handling &Storage This protein is overexpressed inThis gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide

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Description

This protein is overexpressed in epithelial mesotheliomas| ovarian cancers and in specific squamous cell carcinomas

Upon binding of thrombopoietin CD110 is dimerized and the JAK family of non-receptor tyrosine kinases

The protein encoded by this gene may form complex with G proteins and stimulate Rho-dependent signals

This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense

This gene includes a very large exon spanning more than 12

PTEN mouse Monoclonal Antibody(9E8), 100ul Liquid Handling &Storage This protein is overexpressed inThis gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide

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