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Epirubicin - CAS# 56420-45-2 Catalog No.:M9815-2 the target protein is polyubiquitinated

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Epirubicin - CAS# 56420-45-2 Catalog No.:M9815-2 the target protein is polyubiquitinatedEpirubicin is an anthracycline drug used for chemotherapy. It can be used in combination with other medications to treat breast cancer in patients who have had surgery to remove the tumor. Similarly to other anthracyclines, epirubicin acts by intercalating DNA strands. Intercalation results in complex formation which inhibits DNA and RNA synthesis. It also triggers DNA cleavage by topoisomerase II, resulting in mechanisms that lead to cell death.

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Description

the target protein is polyubiquitinated by IAPs

This may lead to the induction of cell cycle arrest and apoptosis in susceptible tumor cells

IRE1α oligomerizes

the BET inhibitor CPI-0610 binds to the acetylated lysine recognition motifs on the bromodomain of BET proteins

Oliceridine is now discontinued since it was recently listed as a controlled substance

Epirubicin - CAS# 56420-45-2 Catalog No.:M9815-2 the target protein is polyubiquitinatedEpirubicin is an anthracycline drug used for chemotherapy. It can be used in combination with other medications to treat breast cancer in patients who have had surgery to remove the tumor. Similarly to other anthracyclines, epirubicin acts by intercalating DNA strands. Intercalation results in complex formation which inhibits DNA and RNA synthesis. It also triggers DNA cleavage by topoisomerase II, resulting in mechanisms that lead to cell death.

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