SB-334867 (base) - an orexin antagonist. CAS# 792173-99-0 size:2mg solid Esserman LJ

Esserman LJ

and other clinically important ABL kinase domain mutants (IC50: 0

Guillausseau PJ

Inhibitors of Hedgehog acyltransferase block Sonic Hedgehog signaling

PD153035 levels in the plasma and tumor rise to 50 and 22 μM within 15 minutes following a single i

SB-334867 (base) - an orexin antagonist. CAS# 792173-99-0 size:2mg solid Esserman LJSB 334867, an orexin antagonist, CAS No. 792173 99 0, is an orexin antagonist. SB 334867 was the first non peptide antagonist developed that is selective for the orexin receptor subtype OX1, with around 50x selectivity for OX1 over OX2 receptors. It has been shown to produce sedative and anorectic effects in animals, and has been useful in characterising the orexinergic regulation of brain systems involved with appetite and sleep, as well as other