Istaroxime Hydrochloride Size:Solid 10 mg 135(5):457-461
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Istaroxime Hydrochloride Size:Solid 10 mg 135(5):457-461Istaroxime, also known as PST 2744, is a positive inotropic agent that mediates its action through inhibition of sodium potassium adenosine triphosphatase (Na+ K+ ATPase). Na+ K+ ATPase inhibition increases intracellular sodium levels, which reverses the driving force of the sodium calcium exchanger, inhibiting calcium extrusion and possibly facilitating calcium entry. Additionally, Istaroxime increases intracellular calcium by improving the efficacy
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