OTSSP167 - CAS# 1431697-89-0 Catalog No.:M9991-10 both of which are critical

both of which are critical for glutamate-mediated signal transduction mechanisms

These inhibitory effects of CH-223191 prevented the expression of cytochrome P450 enzymes

Smiles: CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)N1C3C(=C4C(O)NC(=O)C4=C4C=3N2C2=CC=CC=C24)C2=CC=CC=C12)NC

Peräniemi S

Hernandez D

OTSSP167 - CAS# 1431697-89-0 Catalog No.:M9991-10 both of which are criticalOTSSP167, also known as OTS167, is an orally available inhibitor of maternal embryonic leucine zipper kinase (MELK) with potential antineoplastic activity. Upon administration, OTS167 binds to MELK, which prevents both MELK phosphorylation and activation; thus inhibiting the phosphorylation of downstream MELK substrates. This may lead to an inhibition of both cell proliferation and survival in MELK expressing tumor cells. Product information CAS