MK-4827 - CAS# 1038915-60-4 92 (benzenesulfonate) de Alwis DP

de Alwis DP

ZOL failed to reduce lung metastasis and in some cases was associated with larger and more numerous metastatic lesions

Bepridil hydrochloride blocks calcium entry through membranous calcium channels of coronary and peripheral vascular smooth muscle

⁸]undecan-5-yl 1H-indole-3-carboxylate

Pharmaceuticals (Basel)

MK-4827 - CAS# 1038915-60-4 92 (benzenesulfonate) de Alwis DPNiraparib, also known as MK4827, is an orally active, potent and selective poly(ADP Ribose) polymerase (PARP) inhibitor that radiosensitizes human lung and breast cancer cells. Niraparib inhibits PARP1 PARP2 with IC50 of 3. 8 nM 2. 1 nM respectively. Niraparib is currently in Phase 3 clinical trials for ovarian cancer and BRCA+ breast cancer. Product information CAS Number: 1038915 60 4 Molecular Weight: 320. 39 Formula: C19H20N4O Synonym: Niraparib