Afuresertib - CAS# 1047644-62-1 Catalog No.:M6803-10 FT-0644594

FT-0644594

Vesnarinone inhibits angiogenesis and tumorigenicity of human oral squamous cell carcinoma cells by suppressing the expression of vascular endothelial growth factor and interleukin-8

CAS Number: 105925-39-1

is a potent inhibitor of ferroptosis with an EC50 ~60 nM

Biochem Biophys Res Commun

Afuresertib - CAS# 1047644-62-1 Catalog No.:M6803-10 FT-0644594Afuresertib, CAS No. 1047644 62 1, also known as GSK 2110183 or GSK 2110183C, is an orally bioavailable inhibitor of the serine threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Afuresertib binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K Akt signaling pathway is