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Tamoxifen citrate AC SGK3 degrader-1 Chemical Name: 3-N-(1-Propylbenzimidazol-2-yl)benzene-1

SKU: 5912613351

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Tamoxifen citrate AC SGK3 degrader-1 Chemical Name: 3-N-(1-Propylbenzimidazol-2-yl)benzene-1Tamoxifen, also known as ICI 46474, is an antagonist of the estrogen receptor in breast tissue via its active metabolite, 4 hydroxytamoxifen. In other tissues such as the endometrium, it behaves as an agonist, and thus may be characterized as a selective estrogen receptor modulator. Tamoxifen is the usual endocrine (anti estrogen) therapy for hormone receptor positive breast cancer in pre menopausal women, and is also a standard in post menopausal

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Description

Chemical Name: 3-N-(1-Propylbenzimidazol-2-yl)benzene-1

PubMed PMID: 27681596

Smiles: CN1CCN(CC1)C1C=CC(=CC=1)NC1=NC2=C(C=N1)C(=O)N(CC=C)N2C1=CC=CC(=N1)C(C)(C)O

de Haven Brandon AK

1% in rats

Tamoxifen citrate AC SGK3 degrader-1 Chemical Name: 3-N-(1-Propylbenzimidazol-2-yl)benzene-1Tamoxifen, also known as ICI 46474, is an antagonist of the estrogen receptor in breast tissue via its active metabolite, 4 hydroxytamoxifen. In other tissues such as the endometrium, it behaves as an agonist, and thus may be characterized as a selective estrogen receptor modulator. Tamoxifen is the usual endocrine (anti estrogen) therapy for hormone receptor positive breast cancer in pre menopausal women, and is also a standard in post menopausal

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