KAN0438757 Size:10mg solid Crew et al (2018) Identification

Crew et al (2018) Identification and characterization of Von Hippel-Lindau-recruiting proteolysis targeting chimeras (PROTACs) of TANK-binding kinase 1

InChi: InChI=1S/C26H31N3O5/c1-4-27-26(32)24-23(18-7-5-17(6-8-18)15-29-9-11-33-12-10-29)25(34-28-24)20-13-19(16(2)3)21(30)14-22(20)31/h5-8

CAS Number: 923596-52-5

1093/infdis/jiw129

Chemical Name: Hydrazinecarboximidamide

KAN0438757 Size:10mg solid Crew et al (2018) IdentificationKAN0438757 is a potent and selective inhibitor of the metabolic kinase PFKFB3 (6 Phosphofructo 2 Kinase Fructose 2,6 Biphosphatase 3) with IC50 of 0. 19 M and 3. 6 M for PFKFB3 and PFKFB4, respectively. Product information CAS Number: 1451255 59 6 Molecular Weight: 447. 43 Formula: C21H18FNO7S Synonym: KAN 0438757 KAN 0438757 Chemical Name: 2 hydroxyethyl 4 ((5' fluoro 2' hydroxy [1,1' biphenyl]) 3 sulfonamido) 2 hydroxybenzoate Smiles: