pardoprunox - CAS# 269718-84-5 nd Library of Histone Demethylase InChiKey: VVZNWYXIOADGSW-UHFFFAOYSA-N

InChiKey: VVZNWYXIOADGSW-UHFFFAOYSA-N

Formula: C20H22O6

PubMed Central PMCID: PMC3813614

InChi: InChI=1S/C26H26N2O2/c1-30-26(29)25(16-22-17-27-24-15-9-8-14-23(22)24)28(18-20-10-4-2-5-11-20)19-21-12-6-3-7-13-21/h2-15

Pirfenidone (PFD) shows its inhibitory effects on the proliferation of HLECs

pardoprunox - CAS# 269718-84-5 nd Library of Histone Demethylase InChiKey: VVZNWYXIOADGSW-UHFFFAOYSA-Npardoprunox, CAS No. 269718 84 5, also known as SLV 308; DU 126891; SME 308, is dopamine D2 5 HT1A receptor agonist potentially for the treatment of Parkinson's disease. It was also being investigated for the treatment of depression and anxiety but these indications appear to have been abandoned. Pardoprunox acts as a D2 (pKi = 8. 1) and D3 receptor (pKi = 8. 6) partial agonist (IA = 50% and 67%, respectively) and 5 HT1A receptor (pKi = 8. 5) full