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After washing in 0.1 M phosphate buffer, the samples were postfixed with 1% osmium tetroxide in the same buffer for 1 h at 4 C

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On the other hand, since carnitine supplementation may increase ACs accumulation, the search for a potential protective agent against VPA-induced hepatotoxicity that both upregulates fatty acid -oxidation in mitochondria and does not cause ACs accumulation is necessary