BMS-833923 - CAS# 1059734-66-5 rtrate) 4R)-4-benzyl-2-hydroxy-4-{[(1S

4R)-4-benzyl-2-hydroxy-4-{[(1S

2-HBA is a potent inducer of NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1) which can also activate caspase-3 and caspase-10

CAS Number: 1268524-71-5

It is an orally administered agent with a similar antimicrobial spectrum to the intravenous agents cefalotin and cefazolin

SDZ-ASM-981

BMS-833923 - CAS# 1059734-66-5 rtrate) 4R)-4-benzyl-2-hydroxy-4-{[(1SBMS 833923, also known as XL 139, is an orally bioavailable small molecule SMO (Smoothened) inhibitor with potential antineoplastic activity. SMO antagonist BMS 833923 inhibits the sonic hedgehog (SHH) pathway protein SMO, which may result in a suppression of the SHH signaling pathway. SMO is a G protein coupled receptor that lies just downstream of the SHH ligand cell surface receptor Patched 1 in the SHH pathway; in the absence of ligand Patched 1