SW-044248 - CAS# 522650-83-5 size:10mg solid RN-1 can abolish long-term memory

RN-1 can abolish long-term memory formation without affecting short-term memory in the novel object recognition (NOR) mouse model

In BaF3 cell lines that stably express FLT3-ITD/N676D

Clin Exp Allergy

309(11):F933-42

Polo-like kinase 1 inhibitor TAK-960 selectively inhibits PLK1

SW-044248 - CAS# 522650-83-5 size:10mg solid RN-1 can abolish long-term memorySW 044248, CAS No. 522650 83 5, is a potent and selective Topoisomerase I inhibitor. SW044248 killed approximately 15% of a panel of 74 NSCLC cell lines and was nontoxic to immortalized human bronchial cell lines. The acute transcriptional response to SW044248 in sensitive HCC4017 cells correlated significantly with inhibitors of topoisomerases and SW044248 inhibited topoisomerase 1 (Top1) but not topoisomerase 2. SW044248 inhibited Top1 differently