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I-BRD9 - Bromodomain Containing Protein 9 (BRD9) Inhibitor. CAS# 1714146-59-4 Catalog No.:M60276-2S 13(15 Pt 1):4538-46

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I-BRD9 - Bromodomain Containing Protein 9 (BRD9) Inhibitor. CAS# 1714146-59-4 Catalog No.:M60276-2S 13(15 Pt 1):4538-46I BRD9, CAS No. 1714146 59 4, is a potent, selective and cell permeable Bromodomain Containing Protein 9 (BRD9) inhibitor with Kd ~1. 9 nM. It has >700 fold selectivity over the BET family and 200 fold over the highly homologous bromodomain containing protein 7 (BRD7). It downregulates CLEC1, DUSP6, FES and SAMSN1 genes in Kasumi 1 cells. I BRD9 is the first selective tool compound available to elucidate the cellular phenotype of BRD9 bromodomain

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Description

13(15 Pt 1):4538-46

2013 Sep 23

27(34):4702-11

HLY78 may weaken the autoinhibition of Axin

Synergistic in vivo antitumor effect of the histone deacetylase inhibitor MS-275 in combination with interleukin 2 in a murine model of renal cell carcinoma

I-BRD9 - Bromodomain Containing Protein 9 (BRD9) Inhibitor. CAS# 1714146-59-4 Catalog No.:M60276-2S 13(15 Pt 1):4538-46I BRD9, CAS No. 1714146 59 4, is a potent, selective and cell permeable Bromodomain Containing Protein 9 (BRD9) inhibitor with Kd ~1. 9 nM. It has >700 fold selectivity over the BET family and 200 fold over the highly homologous bromodomain containing protein 7 (BRD7). It downregulates CLEC1, DUSP6, FES and SAMSN1 genes in Kasumi 1 cells. I BRD9 is the first selective tool compound available to elucidate the cellular phenotype of BRD9 bromodomain

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