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BAY K 8644 206 GSK-2981278 robustly inhibits RORγ-mediated cytokine

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BAY K 8644 206 GSK-2981278 robustly inhibits RORγ-mediated cytokineBay K 8644 is a potent selective activator of L type Ca2 channel with IC50 of 173 nM Product information CAS Number: 71145 03 4 Molecular Weight: 356. 30 Formula: C16H15F3N2O4 Chemical Name: methyl 2,6 dimethyl 5 nitro 4 [2 (trifluoromethyl)phenyl] 1,4 dihydropyridine 3 carboxylate Smiles: COC(=O)C1C(C(=C(C)NC=1C)[N+]([O ])=O)C1=CC=CC=C1C(F)(F)F InChiKey: ZFLWDHHVRRZMEI UHFFFAOYSA N InChi: InChI=1S C16H15F3N2O4 c1 8 12(15(22)25 3)13(14(21(23)24)9(2)20

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Description

GSK-2981278 robustly inhibits RORγ-mediated cytokine production at both the mRNA and protein level

27(1):281-5

PubMed Central PMCID: PMC3101825

Vazquez-Carrera M

Ortiz-Ruiz MJ

BAY K 8644 206 GSK-2981278 robustly inhibits RORγ-mediated cytokineBay K 8644 is a potent selective activator of L type Ca2 channel with IC50 of 173 nM Product information CAS Number: 71145 03 4 Molecular Weight: 356. 30 Formula: C16H15F3N2O4 Chemical Name: methyl 2,6 dimethyl 5 nitro 4 [2 (trifluoromethyl)phenyl] 1,4 dihydropyridine 3 carboxylate Smiles: COC(=O)C1C(C(=C(C)NC=1C)[N+]([O ])=O)C1=CC=CC=C1C(F)(F)F InChiKey: ZFLWDHHVRRZMEI UHFFFAOYSA N InChi: InChI=1S C16H15F3N2O4 c1 8 12(15(22)25 3)13(14(21(23)24)9(2)20

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