Y15 481585 Molecular Weight: 406

Molecular Weight: 406

ABT-199 was used at 0

Combining PDMP and GNF-2 eliminated transplanted-CML-T315I-mutants in vivo and dose dependently sensitized primary cells from CML T315I patients to GNF-2-induced proliferation inhibition and apoptosis

InChiKey: AXNUEXXEQGQWPA-UHFFFAOYSA-N

Wahiduzzaman M

Y15 481585 Molecular Weight: 406Y15 hydrochloride, also known as FAK Inhibitor 14, is a direct FAK autophosphorylation inhibitor, blocking phosphorylation of Y397 with an IC50 value of about 1 M. Y15 decreases viability, clonogenicity, and cell attachment in thyroid cancer cell lines and synergizes with targeted therapeutics. Y15 was shown to decrease cancer growth in vitro and in vivo. Product information CAS Number: 4506 66 5 Molecular Weight: 174. 63 Formula: C6H11ClN4 Synonym: