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Ryuvidine - Lysine Methyltransferase SETD8 Inhibitor. CAS# 265312-55-8 size:2 mg solid CC1C=CSC=1C(=CCCN1C[C@@H](CCC1)C(O)=O)C1SC=CC=1C

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Ryuvidine - Lysine Methyltransferase SETD8 Inhibitor. CAS# 265312-55-8 size:2 mg solid CC1C=CSC=1C(=CCCN1C[C@@H](CCC1)C(O)=O)C1SC=CC=1CRyuvidine, CAS No. 265312 55 8, is an inhibitor of SETD8 with cellular activity. It also acts as a CDK4 inhibitor and inducer of the DNA damage response. Product information CAS Number: 265312 55 8 Molecular Weight: 284. 33 Formula: C15H12N2O2S Chemical Name: 2 methyl 5 (p tolylamino)benzo[d]thiazole 4,7 dione Smiles: CC1C=CC(=CC=1)NC1=CC(=O)C2SC(C)=NC=2C1=O InChiKey: HFPLHASLIOXVGS UHFFFAOYSA N InChi: InChI=1S C15H12N2O2S c1 8 3 5 10(6 4 8)17 11 7

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Description

CC1C=CSC=1C(=CCCN1C[C@@H](CCC1)C(O)=O)C1SC=CC=1C

J Biol Chem

TUNEL assay and the analysis of Caspase 3/7 and PARP indicated that BGT226 induced cancer cell death through an apoptosis independent pathway

PubMed Central PMCID: PMC5497932

Lengauer C

Ryuvidine - Lysine Methyltransferase SETD8 Inhibitor. CAS# 265312-55-8 size:2 mg solid CC1C=CSC=1C(=CCCN1C[C@@H](CCC1)C(O)=O)C1SC=CC=1CRyuvidine, CAS No. 265312 55 8, is an inhibitor of SETD8 with cellular activity. It also acts as a CDK4 inhibitor and inducer of the DNA damage response. Product information CAS Number: 265312 55 8 Molecular Weight: 284. 33 Formula: C15H12N2O2S Chemical Name: 2 methyl 5 (p tolylamino)benzo[d]thiazole 4,7 dione Smiles: CC1C=CC(=CC=1)NC1=CC(=O)C2SC(C)=NC=2C1=O InChiKey: HFPLHASLIOXVGS UHFFFAOYSA N InChi: InChI=1S C15H12N2O2S c1 8 3 5 10(6 4 8)17 11 7

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