Tariquidar 126(ZZ) Smiles: CC1=CC2C(=CC=CC=2C(N)=O)N1C1=NC2CCOCC=2C(NCC2C=CC=CC=2)=N1
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Tariquidar 126(ZZ) Smiles: CC1=CC2C(=CC=CC=2C(N)=O)N1C1=NC2CCOCC=2C(NCC2C=CC=CC=2)=N1Tariquidar, also known as XR9576, is a P glycoprotein (P gp) inhibitor undergoing research as an adjuvant against multidrug resistance in cancer. Tariquidar non competitively binds to the p glycoprotein transporter, thereby inhibiting transmembrane transport of anticancer drugs. Inhibition of transmembrane transport may result in increased intracellular concentrations of an anticancer drug, thereby augmenting its cytotoxicity. Product information CAS
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