PROTAC BRD9 Degrader-1 tin) IC50 value: Target: cathepsin K

IC50 value: Target: cathepsin K The cathepsin K inhibitor AAE-581 (balicatib) as the most advanced of them passed Phase II clinical trials in 2005

CP-10 is a PROTAC with highly selective

2013 May 15

a novel long-acting FGF21 mimetic

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PROTAC BRD9 Degrader-1 tin) IC50 value: Target: cathepsin KPROTAC BRD9 Degrader 1 is a lead PROTAC BRD9 chemical degrader (IC50=13. 5 nM), which can be used as a selective probe useful for the study of BAF complex biology. Product information CAS Number: 2097971 01 0 Molecular Weight: 903. 98 Formula: C42H45N7O12S2 Chemical Name: 2 (4 {2 [N (1, 1 dioxo 1 thian 4 yl)carbamimidoyl] 5 methyl 4 oxo 4H, 5H thieno[3, 2 c]pyridin 7 yl} 2 methoxyphenoxy) N [4 (2 {[2 (2, 6 dioxopiperidin 3 yl) 1, 3 dioxo 2, 3 dihydro