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YM 254890 60308 67(8):3912-8
YM 254890 60308 67(8):3912-8
YM 254890 60308 67(8):3912-8
YM 254890 60308 67(8):3912-8

YM 254890 60308 67(8):3912-8

SKU: 85455695992

4.4
USD907.50 USD930.50

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YM 254890 60308 67(8):3912-8G protein inhibitor. Potently inhibits Gq 11 heterotrimeric G protein signaling. Inhibits ATP UTP induced Ca2+ increase in HCAE cells expressing P2Y2 receptor (IC50 = 50 nM); carbachol induced production of IP1 in CHO cells expressing M1 receptor (IC50 = 95 nM); and ADP induced Ca2+ increase in platelets, in vitro (IC50 = 2 M). Also inhibits Gs induced cAMP elevation and G protein coupled MAPK ERK signaling. Product information CAS Number: 568580 02 9

Store: clickpoint.com.au · Domain: clickpoint.com.au

Description

67(8):3912-8

Chemical Name: 2-(4-ethylphenoxy)-N-(4-fluoro-3-nitrophenyl)-acetamide

Harmange JP

1080/01902148

3-[(2-methylphenyl)methylsulfanyl]-6-pyridin-2-ylpyridazine

YM 254890 60308 67(8):3912-8G protein inhibitor. Potently inhibits Gq 11 heterotrimeric G protein signaling. Inhibits ATP UTP induced Ca2+ increase in HCAE cells expressing P2Y2 receptor (IC50 = 50 nM); carbachol induced production of IP1 in CHO cells expressing M1 receptor (IC50 = 95 nM); and ADP induced Ca2+ increase in platelets, in vitro (IC50 = 2 M). Also inhibits Gs induced cAMP elevation and G protein coupled MAPK ERK signaling. Product information CAS Number: 568580 02 9

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