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S3I-201 - CAS# 501919-59-1 254 cAC10-L1-MMAF4 has an MTD of

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S3I-201 - CAS# 501919-59-1 254 cAC10-L1-MMAF4 has an MTD ofS3I 201, also known as NSC 74859, CAS No. 501919 59 1, is a cell permeable Stat3 inhibitor that binds to the Stat3 SH2 domain, prevents Stat3 phosphorylation activation, dimerization, and DNA binding. Product information CAS Number: 501919 59 1 Molecular Weight: 365. 36 Formula: C16H15NO7S Synonym: NSC 74859 Chemical Name: 2 hydroxy 4 (2 (tosyloxy)acetamido)benzoic acid Smiles: CC1C=CC(=CC=1)S(=O)(=O)OCC(=O)NC1=CC(O)=C(C=C1)C(O)=O InChiKey:

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Description

cAC10-L1-MMAF4 has an MTD of 50 mg/kg in mice and 15 mg/kg in rats

Hedgehog partial agonism drives Warburg-like metabolism in muscle and brown fat

injection of S3I-201 (NSC-74859) or vehicle every 2 or every 3 days for 2 weeks

acetyl-transferase protein NAT10 was identified as the target of Remodelin that mediated nuclear shape rescue in laminopathic cells via microtubule reorganization

NU7026 synergistically sensitizes I83 cells to Chlorambucil (CLB) 3

S3I-201 - CAS# 501919-59-1 254 cAC10-L1-MMAF4 has an MTD ofS3I 201, also known as NSC 74859, CAS No. 501919 59 1, is a cell permeable Stat3 inhibitor that binds to the Stat3 SH2 domain, prevents Stat3 phosphorylation activation, dimerization, and DNA binding. Product information CAS Number: 501919 59 1 Molecular Weight: 365. 36 Formula: C16H15NO7S Synonym: NSC 74859 Chemical Name: 2 hydroxy 4 (2 (tosyloxy)acetamido)benzoic acid Smiles: CC1C=CC(=CC=1)S(=O)(=O)OCC(=O)NC1=CC(O)=C(C=C1)C(O)=O InChiKey:

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