RTA-408 Catalog No.:M8670-2 14bS)-11-cyano-2

14bS)-11-cyano-2

and the IC50s of Y-27632 and Y-33075 for PKC are 9

tert-Butyl ((S)-1-(((S)-1-cyclohexyl-2-((S)-2-(4-(3-hydroxybenzoyl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)amino)-1-oxopropan-2-yl)(methyl)carbamate

9 g of NaCl in 100 mL distilled water to make a clear 0

This compound

RTA-408 Catalog No.:M8670-2 14bS)-11-cyano-2Omaveloxolone, also known as RTA 408, is a member of the synthetic oleanane triterpenoid class of compounds and an activator of nuclear factor erythroid 2 [NF E2] related factor 2 (Nrf2, Nfe2l2), with potential chemopreventive activity. Upon administration, RTA 408 activates the cytoprotective transcription factor Nrf2. In turn, Nrf2 translocates to the nucleus, dimerizes with a small Maf protein (sMaf), and binds to the antioxidant response element