CAL-130 - CAS# 1431697-74-3 Size:Solid 10 mg altered cellular oxygen consumption rate

altered cellular oxygen consumption rate and induced production of pAMPK

Martindale C

Neurite outgrowth induced by expression of the mALKR1279Q mutant is completely inhibited at 30 nM NVP-TAE684

BRaf and CRaf isoforms with similar affinity in cells with activating mutations of BRaf or KRas

CI994 (Tacedinaline)

CAL-130 - CAS# 1431697-74-3 Size:Solid 10 mg altered cellular oxygen consumption rateCAL 130 is a potent and selective PI3K gamma and delta inhibitor with potential anticancer activity. Constitutive phosphoinositide 3 kinase (PI3K) Akt activation is common in T cell acute lymphoblastic leukemia (T ALL). Although four distinct class I PI3K isoforms (, , , ) could participate in T ALL pathogenesis, none has been implicated in this process. In the absence of PTEN phosphatase tumor suppressor function, PI3K or PI3K alone can support