Daidzein-2c - Osteogenic Modulator. CAS# 97846-18-9 0154 2016 Dec 12

2016 Dec 12

CAS Number: 1380548-02-6

(2014) Proc Natl Acad Sci USA

CB-5083 was dosed to mice orally at 25-100 mg/Kg once or twice per day

is a potent and selective small molecule that enhances hepatocyte functions and promotes the differentiation and maturation of iPSC-derived hepatocytes toward a more mature phenotype in vitro

Daidzein-2c - Osteogenic Modulator. CAS# 97846-18-9 0154 2016 Dec 12Daidzein 2c, CAS No. 97846 18 9, is a potent synthetic daidzein analog, has osteogenic induction potentials on human Mesenchymal Stem Cells (MSC). Human bone marrow derived mesenchymal stem cells from three different donors were treated with Daidzein 2c and shown to exhibit enhanced osteogenesis when compared to daidzein or estrogen treatment. The enhanced osteogenic induction by Daidzein 2c resulted in increased osterix (Sp7), alkaline phosphatase