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L-165041 Size:Solid 10 mg SW044248 is a non-canonical Top1

SKU: 97061029173

4.1
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L-165041 Size:Solid 10 mg SW044248 is a non-canonical Top1L 165041, also known as L 165,041, is a potent and selective agonist of the nuclear receptor PPAR (Ki = 9 nM, EC50 = ~500 nM for hPPAR ). L 165041 promotes VEGF mRNA stabilization in HPV18 harboring HeLa cells through a receptor independent mechanism. L 165041 inhibits VEGF induced angiogenesis, but the antiangiogenic effect is not related to PPAR. L 165041 inhibits rat vascular smooth muscle cell proliferation and migration via inhibition of cell

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Description

SW044248 is a non-canonical Top1 inhibitor

53)41(52)56-7

CAS Number: 893990-34-6

It shows more than 100-fold selectivity for mTOR relative to PI3Kα

once daily or twice daily orally)

L-165041 Size:Solid 10 mg SW044248 is a non-canonical Top1L 165041, also known as L 165,041, is a potent and selective agonist of the nuclear receptor PPAR (Ki = 9 nM, EC50 = ~500 nM for hPPAR ). L 165041 promotes VEGF mRNA stabilization in HPV18 harboring HeLa cells through a receptor independent mechanism. L 165041 inhibits VEGF induced angiogenesis, but the antiangiogenic effect is not related to PPAR. L 165041 inhibits rat vascular smooth muscle cell proliferation and migration via inhibition of cell

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