eIF4G(Phospho-Ser1108) Rabbit Polyclonal Antibody, 50ul Fluorescent Staining This protein also cleaves neuropeptides

This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides

This gene is widely expressed in many tissues

which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain

where the mature form is found

Transcript variants utilizing alternative polyA signals and alternative 5'-terminal exons exist but all encode the same protein

eIF4G(Phospho-Ser1108) Rabbit Polyclonal Antibody, 50ul Fluorescent Staining This protein also cleaves neuropeptidesThe protein encoded by this gene is a component of the multi subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome which is a rate limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP dependent unwinding of 5' terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains