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F100A Rabbit Polyclonal Antibody, 50ul Cell Culture & Maintenance a LAP homodimer

SKU: 39290276499

4.6
USD185.00 USD231.00

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F100A Rabbit Polyclonal Antibody, 50ul Cell Culture & Maintenance a LAP homodimer

Store: clickpoint.com.au · Domain: clickpoint.com.au

Description

a LAP homodimer

During T-cell activation| this protein is actively removed from the T-cell-APC (antigen-presenting cell) contact site| suggesting a negative regulatory role in adaptive immune response

In addition| the CXXC domain of this protein has been shown to bind unmethylated CpG dinucleotides| localize to promoters and CpG islands| and interact with the catalytic domain of methylcytosine dioxygenase ten-eleven-translocation 2| an iron and alpha-ketoglutarate-dependent dioxygenase that modifies the methylation status of DNA

Mutations in this gene result in mucopolysaccharidosis type VII

The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs

F100A Rabbit Polyclonal Antibody, 50ul Cell Culture & Maintenance a LAP homodimer

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